The article is a supplementary material for a study on fluid responsiveness and venous congestion in patients with sepsis and respiratory failure. ​
The study aimed to assess fluid responsiveness and venous congestion using various clinical variables and ultrasound scores. ​
The study examined the prevalence of venous congestion signals in mechanically ventilated patients with acute circulatory dysfunction within 24 hours of ICU admission. ​
The prevalence of venous congestion signals was high and independent of fluid responsiveness status. ​
There was no association between fluid balance or diagnosis and the presence of venous congestion signals. ​
More than half of the fluid responsive patients in the study could be considered potentially fluid intolerant as they had at least one venous congestion signal. ​
This subset of patients had higher odds of developing acute kidney injury at seven days. ​
The study suggests that clinicians should be aware of the potential dangers of fluid administration even in fluid responsive patients. ​
The study used different techniques to assess venous congestion, including central venous pressure, lung ultrasound score, and venous excess ultrasound score. ​
Lateral E/e’ and lung ultrasound score were used as surrogates for ventricular filling pressures and showed correlations with venous congestion signals. ​
The high prevalence of venous congestion in fluid responsive patients at ICU admission is a paradox that requires further investigation. ​
The study calls for future research to assess the evolution of fluid responsiveness and venous congestion throughout the resuscitation process in high-risk contexts. ​
Integration of these concepts into resuscitation algorithms could provide new tools for personalized resuscitation and avoid adverse events.Â
https://ccforum.biomedcentral.com/articles/10.1186/s13054-024-04834-1